Using an Isolated Rat Kidney Model to Identify Kidney Origin Proteins in Urine

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Using an Isolated Rat Kidney Model to Identify Kidney Origin Proteins in Urine

The use of targeted proteomics to identify urinary biomarkers of kidney disease in urine can avoid the interference of serum proteins. It may provide better sample throughput, higher sensitivity, and specificity. Knowing which urinary proteins to target is essential. By analyzing the urine from perfused isolated rat kidneys, 990 kidney origin proteins with human analogs were identified in urine...

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Bradley, H. C. (1938). Phy8iol. Rev. 18, 173. Graseman, W., Hannig, K. & Knedel, M. (1951). Dt8ch. med. W8chr. 73, 333. Heidenhain, M. (1907). Plasma und Zelle, vol. 1, p. 449. Jena: Fisher. King, E. J. (1951). Microanalysis in Medical Biochemistry, 2nd ed., p. 47. London: Churchill. Leuthardt, F. & Koller, F. (1934). Helv. chim. ada, 17, 1030. Markham, R. (1942). Biochem. J. 42, 462. Pozzi, L....

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2013

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0066911